Premecz G, Markovits A, Földes I
Microbiological Research Group, B. Johan National Institute of Hygiene, Budapest, Hungary.
Acta Microbiol Hung. 1993;40(2):131-40.
Experimental results suggest that protein kinase C (PK-C) may play a substantial role in the action of IFNs, but the precise biochemical pathway remains unknown. Recent evidences reveal the complexity of the mechanism of IFN-action and show that the IFN-alpha, -beta and -gamma induced pathways are overlapping. We briefly discuss what is known in this field and suggest a way in which the contrasting views might be reconciled.
实验结果表明，蛋白激酶C（PK-C）可能在干扰素的作用中发挥重要作用，但确切的生化途径仍不清楚。最近的证据揭示了干扰素作用机制的复杂性，并表明α-、β-和γ-干扰素诱导的途径相互重叠。我们简要讨论了该领域的已知情况，并提出了一种调和不同观点的方法。
