Hoşal N, Turan E, Aras T
Department of Otolaryngology-Head and Neck Surgery, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
Arch Otolaryngol Head Neck Surg. 1994 Jun;120(6):659-61. doi: 10.1001/archotol.1994.01880300073011.
Myocutaneous flaps are used widely in the surgical treatment of advanced cancers, which in the past had been thought to be inoperable. Tumor recurrences are expected more frequently in these patients. Recurrent tumors may spread locally and to the regional areas via lymphatics and vessels. However, the lymphatic spread may differ in cases where myocutaneous flaps are used for reconstruction. This study is based on five patients with head and neck cancer who underwent reconstruction with myocutaneous flaps. Technetium Tc99m-labeled dextran was used to demonstrate the lymphatic flow, and technetium Tc99m rhenium sulfur colloid was used to show the lymph nodes of the neck and pectoralis major myocutaneous flap. Our findings show that the newly formed lymphatics do not pierce the fibrotic border of the donor and recipient sides. Lymphatic metastasis may occur to the internal mammary nodes through the myocutaneous flap only after recurrent tumors have invaded the myocutaneous flap directly.
肌皮瓣广泛应用于晚期癌症的外科治疗,这些癌症在过去被认为无法手术切除。预计这些患者更容易出现肿瘤复发。复发性肿瘤可能通过淋巴管和血管在局部和区域扩散。然而,在使用肌皮瓣进行重建的情况下,淋巴扩散可能有所不同。本研究基于5例接受肌皮瓣重建的头颈癌患者。使用锝Tc99m标记的葡聚糖来显示淋巴流动,使用锝Tc99m硫化铼胶体来显示颈部和胸大肌肌皮瓣的淋巴结。我们的研究结果表明,新形成的淋巴管不会穿透供体和受体侧的纤维化边界。只有在复发性肿瘤直接侵犯肌皮瓣后,淋巴转移才可能通过肌皮瓣转移至内乳淋巴结。