低氧血症与胎儿血红蛋白合成增加。
Hypoxemia and increased fetal hemoglobin synthesis.
作者信息
Bard H, Fouron J C, Gagnon C, Gagnon J
机构信息
Neonatology Service, St. Justine's Hospital, Montreal, Quebec, Canada.
出版信息
J Pediatr. 1994 Jun;124(6):941-3. doi: 10.1016/s0022-3476(05)83188-9.
PMID:7515415
Abstract
Fetal hemoglobin (HbF) synthesis in children with congenital cyanotic heart disease was compared that in normal children. Children with hypoxemia had higher levels of hemoglobin, total HbF, and HbF synthesis. In these children there was also an inverse correlation between HbF synthesis and oxygen content, as well as between HbF synthesis and hemoglobin concentration. Thus hypoxemia increases HbF synthesis.
摘要
对患有先天性紫绀型心脏病的儿童与正常儿童的胎儿血红蛋白（HbF）合成情况进行了比较。低氧血症患儿的血红蛋白、总HbF及HbF合成水平较高。在这些患儿中，HbF合成与氧含量之间以及HbF合成与血红蛋白浓度之间也呈负相关。因此，低氧血症会增加HbF合成。
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