Thorn L, Arnold W, Schinko I, Wetzstein R
Arch Otorhinolaryngol. 1978 Sep 28;221(2):123-33. doi: 10.1007/BF00455883.
In early stages of fetal development (36th day, 3rd turn) the thickening of the epithelium at the basal side of the cochlear duct forms two ridges. Later in fetal development the laterally situated lesser epithelial ridge forms the major part of the organ of Corti, whereas the medially situated greater epithelial ridge contributes only a small part to this organ. The medial part of the greater ridge consists of the columnar inner supporting cells, which bear a border of closely packed microvilli at their upper surface. Up to the time of the opening of the internal spiral sulcus in the 48th day of fetal development, there is a close spacial relationship between microvilli and filaments of the tectorial membrane. We conclude that the inner supporting cells contribute to the formation of the tectorial membrane. However, thus far we cannot entirely exclude a different possibility, that the inner supporting cells absorb material of the tectorial membrane. During the opening of the sulcus spiralis internus the inner supporting cells become considerably smaller, some of them undergo complete destruction by cytolysis, with pyknosis and karyorrhexis.
在胎儿发育早期(第36天,第3个转折期),蜗管基底侧的上皮增厚形成两条嵴。在胎儿发育后期,位于外侧的较小上皮嵴形成了柯蒂氏器的主要部分,而位于内侧的较大上皮嵴仅对该器官有一小部分贡献。较大嵴的内侧部分由柱状内支持细胞组成,这些细胞在其上表面有一层紧密排列的微绒毛边界。直到胎儿发育第48天内螺旋沟开放时,微绒毛与盖膜细丝之间存在密切的空间关系。我们得出结论,内支持细胞有助于盖膜的形成。然而,到目前为止,我们不能完全排除另一种可能性,即内支持细胞吸收盖膜的物质。在内螺旋沟开放期间,内支持细胞变得明显更小,其中一些细胞通过细胞溶解而完全破坏,出现核固缩和核碎裂。