Del Guercio R, Conti G, De Buono A F, Gentile S, Saponara A, Leone C
Boll Soc Ital Biol Sper. 1978 Nov 15;54(21):2078-81.
We have studied PRA levels in 10 healthy subjects compared with 10 patients affected with essential hypertension (with low PRA) on venous blood samples collected after 8 hours of rest and after 15-20 minutes of slow plain walk. Contemporarely we have taken up arterious pression levels in each class of subjects of these studies. No significant differences of PRA are demonstrable in healthy subjects and in patients affected with essential hypertension. Postural changes in hypertension produces significant rise of PRA, not related to arterial pressure.
我们研究了10名健康受试者与10名原发性高血压患者(肾素活性低)的肾素活性(PRA)水平,静脉血样本是在休息8小时后以及缓慢平地行走15 - 20分钟后采集的。同时,我们还测量了这些研究中每组受试者的动脉血压水平。健康受试者和原发性高血压患者的PRA无显著差异。高血压患者的体位变化会导致PRA显著升高,且与动脉血压无关。