Urakov N N, Veriasova G V, Sokov B N, Kavyzina L I, Sergeeva N L
Vestn Ross Akad Med Nauk. 1994(4):46-51.
The paper deals with the problem pertaining to immunotoxins which consist of two components, namely: catalytic (effector) and receptor-binding (ligand) ones. The immunotoxins are promising pharmaceutical drugs of a new generation, which are successfully used in clinical practice to treat tumor diseases, allergy, AIDS, and to transplant organs and tissues. Immunotoxins for the therapy of diabetes, autoimmune diseases, and bacterial, viral, and parasitic infections are being developed.
本文探讨了与免疫毒素相关的问题,免疫毒素由两个部分组成,即催化(效应)部分和受体结合(配体)部分。免疫毒素是新一代有前景的药物,已成功用于临床治疗肿瘤疾病、过敏、艾滋病以及器官和组织移植。目前正在研发用于治疗糖尿病、自身免疫性疾病以及细菌、病毒和寄生虫感染的免疫毒素。