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[间变性癌的鉴别诊断与治疗]

[Differential diagnosis and treatment of metatypic cancer].

作者信息

Molochkov V A, Poliakov P Iu, Fradkin V G, Kazantseva I A, Snarskaia E S

出版信息

Vestn Ross Akad Med Nauk. 1994(4):60-2.

PMID:7516771
Abstract

Fifty one patients with metatypic carcinoma (MC), 10 with basalioma, and 10 with squamous cell carcinoma were clinically and immuno-morphologically studied. There were great differences in the localization of basal cell antigen in the epidermis during MC, basalioma, squamous carcinoma of the skin. Expression of fixed immunoglobulins A, M, G in tumor tissues revealed no significant differences. Fifty one patients underwent a complex treatment with prospidin in a total dose of 3,000-3,500 mg (in a daily dose of 100 mg) followed by near-focus X-ray therapy in a total dose of 3,000 Gy (a single dose being 500 Gy). Good immediate and late (the duration of the follow-up was as long as 5 years) results were obtained.

摘要

对51例化生癌(MC)患者、10例基底细胞癌患者和10例鳞状细胞癌患者进行了临床和免疫形态学研究。在MC、基底细胞癌、皮肤鳞状细胞癌中,基底细胞抗原在表皮中的定位存在很大差异。肿瘤组织中固定免疫球蛋白A、M、G的表达无显著差异。51例患者接受了总量为3000 - 3500mg(每日剂量100mg)的丙帕他莫复合治疗,随后进行总量为3000Gy(单次剂量500Gy)的近聚焦X线治疗。获得了良好的近期和远期(随访时间长达5年)效果。

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