顺二氯二氨合铂（II）与阿霉素联合治疗晚期卵巢癌
cis-Dichlorodiammineplatinum(II) and adriamycin treatment of advanced ovarian cancer.
作者信息
Briscoe K E, Pasmantier M W, Ohnuma T, Kennedy B J
出版信息
Cancer Treat Rep. 1978 Dec;62(12):2027-30.
PMID:751711
Abstract
Treatment with a combination of adriamycin (ADM) and cis-dichlorodiammineplatinum(II) (DDP) has been evaluated in 24 patients with advanced ovarian cancer. Twenty patients had received prior chemotherapy and/or radiation therapy. Objective remissions were seen in ten patients. The usual toxic manifestations of ADM and DDP were observed. It is concluded that the combination is effective therapy for ovarian cancer. Further investigation of this combination versus single agents is warranted.
摘要
对24例晚期卵巢癌患者采用阿霉素（ADM）和顺二氯二氨铂（II）（DDP）联合治疗进行了评估。20例患者曾接受过化疗和/或放疗。10例患者出现客观缓解。观察到了ADM和DDP常见的毒性表现。结论是该联合治疗对卵巢癌是有效的疗法。有必要进一步研究这种联合治疗与单药治疗的对比情况。
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