John M E, Martines E, Cvintal T, Mellor Filho A, Soter F, Barbosa de Sousa M C, Boleyn K L, Ballew C
John-Kenyon Eye Research Foundation, Jeffersonville, IN 47130.
J Refract Corneal Surg. 1994 Mar-Apr;10(2 Suppl):S206-10.
We present 3 eyes that underwent photorefractive keratectomy (PRK) for residual myopia after penetrating keratoplasty, and 1 eye that was treated for recurrent granular dystrophy and myopia following penetrating keratoplasty. The 3 refractive eyes experienced improvements in visual acuity and refractive error through 3 months postoperative, but exhibited regression of effect after 6 months postoperative. One eye also exhibited substantial corneal haze at three months postoperative that was not responsive to steroid retreatment. The eye with granular dystrophy obtained symptomatic relief as well as improvement in vision. We tentatively conclude that the corneal transplant reacts to photorefractive keratectomy in much the same way as a normal cornea. Eyes with substantial degrees of post-graft myopia exhibit regression of refractive effect, much like high myopes following primary photorefractive keratectomy. Photorefractive was unable to prevent the recurrence of granular dystrophy in the transplanted tissue. The eyes reported here achieved only modest long-term visual and refractive improvements.
我们报告了3只因穿透性角膜移植术后残余近视而接受准分子激光角膜切削术（PRK）的眼睛，以及1只因穿透性角膜移植术后复发性颗粒状角膜营养不良和近视而接受治疗的眼睛。这3只接受屈光手术的眼睛在术后3个月时视力和屈光不正有所改善，但在术后6个月时效果出现了回退。其中1只眼睛在术后3个月时还出现了严重的角膜混浊，对类固醇再治疗无反应。患有颗粒状角膜营养不良的那只眼睛症状得到缓解，视力也有所改善。我们初步得出结论，角膜移植对准分子激光角膜切削术的反应与正常角膜大致相同。移植后有高度近视的眼睛屈光效果会回退，这与初次接受准分子激光角膜切削术的高度近视患者情况很相似。准分子激光角膜切削术无法防止移植组织中颗粒状角膜营养不良的复发。这里报告的这些眼睛仅在长期视觉和屈光方面取得了适度改善。
