Madjar H, Prömpeler H, Wolfahrt R, Bauknecht T, Pfleiderer A
Universitäts-Frauenklinik Freiburg.
Ultraschall Med. 1994 Apr;15(2):69-73. doi: 10.1055/s-2007-1004011.
The recent development of high-quality colour Doppler instruments allows flow detection in small vessels below the resolution of B-mode imaging. Therefore, Doppler is now frequently used for flow detection in tumours. For breast examinations, CW Doppler has been in use for many years, which allows a sufficient definition of diagnostic criteria. Nevertheless, it is surprising that new studies using colour Doppler try to define different diagnostic criteria. To characterise the vascularity of breast lesions by colour Doppler we investigated 127 symptomatic patients. In 54 carcinomas the average flow velocity was 32 cm/s and 12.6 cm/s in 73 benign conditions (p > 0.0001). Total tumour vascularisation was characterised by a new parameter: the sum of all flow velocities in all tumour vessels. In carcinomas the mean total flow as 197.9 cm/s, and 52.7 cm/s in benign pathologies (p > 0.0001). Mean RI (resistance index) and PI (pulsatility index) were calculated to describe the flow profiles. The wide variation did not allow for a differentiation between benign and malignant lesions.
近期高质量彩色多普勒仪器的发展使得在B模式成像分辨率以下的小血管中进行血流检测成为可能。因此，多普勒现在常用于肿瘤中的血流检测。在乳腺检查中，连续波多普勒已经使用多年，它能够充分定义诊断标准。然而，令人惊讶的是，使用彩色多普勒的新研究试图定义不同的诊断标准。为了通过彩色多普勒表征乳腺病变的血管分布，我们对127例有症状的患者进行了研究。在54例癌中，平均流速为32 cm/s，在73例良性病变中为12.6 cm/s（p>0.0001）。总肿瘤血管分布通过一个新参数来表征：所有肿瘤血管中所有流速的总和。在癌中，平均总流速为197.9 cm/s，在良性病变中为52.7 cm/s（p>0.0001）。计算平均阻力指数（RI）和搏动指数（PI）以描述血流情况。较大的差异不允许区分良性和恶性病变。
