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[产生甲胎蛋白的肾上腺肝样癌:一例报告]

[Adrenal hepatoid carcinoma producing alpha-fetoprotein: a case report].

作者信息

Yoshioka M, Ihara H, Shima H, Mori Y, Ikoma F, Ueno Y, Uematsu K

机构信息

Department of Urology, Hyogo College of Medicine.

出版信息

Hinyokika Kiyo. 1994 May;40(5):411-4.

PMID:7517622
Abstract

A case of left adrenal hepatoid carcinoma is reported. The patient was a 57-year-old male and his chief complaint was general fatigue. Preoperative laboratory data showed markedly increased levels of alpha-fetoprotein (AFP) (30,500 ng/ml) and PIVKA-II (3.01 AU/ml). Both computed tomography (CT) and magnetic resonance computed tomography (MRCT) showed left adrenal tumor (8 x 5 cm). Angiography showed hypervascular tumor over the upper pole of the left kidney. Thoracoabdominal nephro-adrenalectomy was performed. Histological examination demonstrated hepatoid carcinoma of the left adrenal gland. AFP was positive in the tumor cells. The levels of both AFP and PIVKA-II dropped to the normal range postoperatively. Hepatoid carcinoma in the urological field is very rare. As hepatoid carcinoma in the Japanese literature in the urological field, there were only 4 cases of renal tumor, 2 cases of renal pelvic tumor, 2 cases of retroperitoneal space and 1 case of urachal tumor. This is the first report of adrenal hepatoid carcinoma in Japan.

摘要

报告一例左肾上腺肝样癌病例。患者为57岁男性,主要诉求为全身乏力。术前实验室检查数据显示甲胎蛋白(AFP)水平显著升高(30,500 ng/ml)及异常凝血酶原(PIVKA-II)水平升高(3.01 AU/ml)。计算机断层扫描(CT)及磁共振计算机断层扫描(MRCT)均显示左肾上腺肿瘤(8×5 cm)。血管造影显示左肾上极肿瘤血运丰富。行胸腹联合肾肾上腺切除术。组织学检查证实为左肾上腺肝样癌。肿瘤细胞中AFP呈阳性。术后AFP及PIVKA-II水平均降至正常范围。泌尿系统领域的肝样癌非常罕见。作为日本文献中泌尿系统领域的肝样癌,仅有4例肾肿瘤、2例肾盂肿瘤、2例腹膜后间隙肿瘤及1例脐尿管肿瘤。这是日本首例肾上腺肝样癌报告。

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