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通过短杆菌肽通道的氙转运证据:一项¹²⁹Xe核磁共振研究。

Evidence of xenon transport through the gramicidin channel: a 129Xe-NMR study.

作者信息

McKim S, Hinton J F

机构信息

Department of Chemistry/Biochemistry, University of Arkansas, Fayetteville 72701.

出版信息

Biochim Biophys Acta. 1994 Jul 13;1193(1):186-98. doi: 10.1016/0005-2736(94)90348-4.

Abstract

Evidence is presented for Xe transport through the gramicidin A channel. This evidence for Xe transport through gramicidin A channels has been obtained using 129Xe-NMR spectroscopy. Three experiments were utilized. The first experiment involved monitoring the change in the chemical shift of 129Xe in the presence of increasing gramicidin A concentration, the second observed the effect on the 129Xe chemical shift with gramicidin A channels photochemically altered by UV light and the third determined the effect of gramicidin A channels blocked by Ba2+ on the 129Xe chemical shift. The results of these three experiments indicate that Xe transports through the gramicidin A channel.

摘要

有证据表明氙可通过短杆菌肽A通道进行转运。关于氙通过短杆菌肽A通道转运的这一证据是利用129Xe核磁共振波谱法获得的。采用了三个实验。第一个实验是监测在短杆菌肽A浓度增加的情况下129Xe化学位移的变化,第二个实验观察了经紫外光光化学改变的短杆菌肽A通道对129Xe化学位移的影响,第三个实验确定了被Ba2+阻断的短杆菌肽A通道对129Xe化学位移的影响。这三个实验的结果表明氙可通过短杆菌肽A通道进行转运。

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