Dgani R, Zalel Y, Biran H, Blickstein I, Caspi B, Weissman A, Shoham Z
Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
Eur J Obstet Gynecol Reprod Biol. 1994 Mar 31;54(1):77-9. doi: 10.1016/0028-2243(94)90084-1.
A 29-year-old nullipara with partial hydatidiform mole at 8 weeks had pre-evacuation hCG levels of 275,000 mIU/ml. Free beta-hCG levels were measured as 3% (normal value below 4%). The patient developed persistent gestational trophoblastic disease, failed to respond to methotrexate and actinomycin D, but has responded to combination chemotherapy with EMA-CO. Such a response to EMA-CO was not reported previously.
一名29岁未生育女性，孕8周时诊断为部分性葡萄胎，清宫术前血hCG水平为275,000 mIU/ml。游离β-hCG水平测定为3%（正常值低于4%）。该患者发生持续性妊娠滋养细胞疾病，对甲氨蝶呤和放线菌素D治疗无效，但对EMA-CO联合化疗有反应。此前未见对EMA-CO如此反应的报道。
