Lisianyĭ I I, Cheren'ko T M, Komissarenko S V, Berezhnoĭ G A, Tukhtiev N Kh, Arustamian R S
Zh Nevrol Psikhiatr Im S S Korsakova. 1993;93(2):50-3.
Data are reported on the content of neurospecific proteins in the blood serum of 87 patients with closed head injuries. It has been established that the method of competent EIA can be used for measuring the content of neurospecific proteins. It has also been shown that their content in the blood depended on the severity of injury: the more severe injury the higher the protein content. Some aspects have been revealed of the blood content of protein 14-3-2 and total myelin protein. The authors discuss a possible diagnostic importance of these proteins in the differential diagnosis of the severity of closed head injuries and in the determination of lesions of the neuroglia and neurons both in mild and grave trauma.
报告了87例闭合性颅脑损伤患者血清中神经特异性蛋白的含量数据。已证实,采用灵敏的酶免疫测定法可用于检测神经特异性蛋白的含量。还表明,它们在血液中的含量取决于损伤的严重程度:损伤越严重,蛋白质含量越高。已揭示了蛋白14-3-2和总髓磷脂蛋白血液含量的某些方面。作者讨论了这些蛋白质在闭合性颅脑损伤严重程度的鉴别诊断以及在轻度和重度创伤中神经胶质和神经元损伤测定方面可能具有的诊断重要性。