Kavraĭskaia I A, Nazarova L A
Biull Eksp Biol Med. 1993 Jan;115(1):21-3.
In the chronic experiments at the end of pregnancy the effects of the infusion to mother of some drugs (trental, reopolyglucin and their combination) on the female of a rabbit and its fetuses normally developed and growth retarded were studied. It was found that changes in the intensity of maternal-placental blood flow, induced by the infusion of drugs to mother lead to the changes of gradient between temperature of fetus and mother, which reflect intensity of feto-placental blood flow and consequently the intensity of fetal heat loss. The possible unfavourable influence of these drugs on fetus temperature regimen and consequently on its metabolic processes under the treatment of placental insufficient and growth retardation have been taken into consideration.
在妊娠末期的慢性实验中，研究了向母体输注某些药物（曲克芦丁、低分子右旋糖酐及其组合）对正常发育和生长迟缓的兔母及其胎儿的影响。发现向母体输注药物引起的母胎血流强度变化会导致胎儿与母体温度梯度的变化，这反映了胎儿-胎盘血流强度，进而反映了胎儿散热强度。已经考虑到这些药物在治疗胎盘功能不全和生长迟缓时可能对胎儿体温调节以及由此对其代谢过程产生的不利影响。
