Thomas M A, Dickinson J D, Melberg N S, Ibanez H E, Dhaliwal R S
Retina Consultants, Ltd, St. Louis, MO 63110.
Ophthalmology. 1994 Aug;101(8):1384-96. doi: 10.1016/s0161-6420(94)31172-9.
The authors report their experience with the surgical removal of subfoveal choroidal neovascularization. Correlations between preoperative characteristics and final postoperative visual acuity are explored.
A retrospective study of 159 consecutive patients was performed between February 1990 and August 1993. Follow-up of 2 or more months was available for 147 eyes: presumed ocular histoplasmosis syndrome, 67 eyes; age-related macular degeneration, 41 eyes; myopia, 10 eyes; multifocal choroiditis, 9 eyes; idiopathic, 8 eyes; angioid streaks, 4 eyes; and miscellaneous, 8 eyes.
Sixty-seven eyes had presumed ocular histoplasmosis syndrome: mean follow-up was 10.5 months. Visual acuity was stable or improved in 56 (83%) eyes and 20/40 or greater in 21 (31%) eyes. Mean interval to best visual acuity was 3 months. A recurrence rate of 37% had no significant effect on final visual outcome (P = 0.952). Forty-one eyes had age-related macular degeneration: mean follow-up was 15 months. Visual acuity was improved in only five (12%) eyes and was 20/40 or greater in only two (5%) eyes. The interval to best visual acuity was 5 months. A recurrence rate of 27% had not significant effect on final visual outcome (P = 0.31). The visual results and recurrence rates for eyes with less common disorders are presented.
The surgical excision of subfoveal choroidal neovascularization may stabilize or improve visual acuity in selected cases. Patients with focal disorders of the retinal pigment epithelium-Bruch's membrane complex appear to have a better surgical outcome than those with diffuse disease.
作者报告其手术切除黄斑下脉络膜新生血管的经验。探讨术前特征与术后最终视力之间的相关性。
对1990年2月至1993年8月期间连续的159例患者进行回顾性研究。147只眼获得了2个月或更长时间的随访:疑似眼组织胞浆菌病综合征67只眼;年龄相关性黄斑变性41只眼;近视10只眼;多灶性脉络膜炎9只眼;特发性8只眼;血管样条纹4只眼;其他8只眼。
67只眼患有疑似眼组织胞浆菌病综合征:平均随访10.5个月。56只(83%)眼视力稳定或提高,21只(31%)眼视力达到20/40或更好。达到最佳视力的平均间隔时间为3个月。37%的复发率对最终视力结果无显著影响(P = 0.952)。41只眼患有年龄相关性黄斑变性:平均随访15个月。仅5只(12%)眼视力提高,仅2只(5%)眼视力达到20/40或更好。达到最佳视力的间隔时间为5个月。27%的复发率对最终视力结果无显著影响(P = 0.31)。还给出了患有较罕见疾病的眼的视力结果和复发率。
黄斑下脉络膜新生血管的手术切除在某些病例中可能使视力稳定或提高。视网膜色素上皮 - 布鲁赫膜复合体局灶性病变的患者手术效果似乎优于弥漫性疾病患者。