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[干扰素治疗对酒精性肝损伤的影响]

[Effects of interferon treatment in alcoholic liver injury].

作者信息

Matsuda Y

机构信息

Dept. Gastroenterology, Kanazawa, Med. University.

出版信息

Nihon Rinsho. 1994 Jul;52(7):1869-74.

PMID:7521433
Abstract

The concentration of Hepatitis C Virus (HCV) in the blood is increased by alcohol drinking and decreased by abstinence. These facts suggested that alcohol abuse may enhance the replication of HCV. The effects of alcohol on HCV replication may be related to increased development of chronic hepatitis to liver cirrhosis and hepatocellular carcinoma in HCV marker positive heavy drinker. These results indicated that HCV positive heavy drinkers must keep abstinence and that these patients have to be treated with interferon.

摘要

饮酒会使血液中丙型肝炎病毒(HCV)的浓度升高,而戒酒则会使其降低。这些事实表明,酗酒可能会增强HCV的复制。酒精对HCV复制的影响可能与HCV标志物阳性的重度饮酒者中慢性肝炎发展为肝硬化和肝细胞癌的几率增加有关。这些结果表明,HCV阳性的重度饮酒者必须戒酒,并且这些患者必须接受干扰素治疗。

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