Busin M, Meller D
University Eye Hospital, Bonn, Germany.
J Refract Corneal Surg. 1994 May-Jun;10(3):357-9.
Map-dot-fingerprint epithelial changes of the cornea have been reported to occur as a consequence of trauma or surgical procedures, such as radial keratotomy.
We describe a case of dot-like changes in the corneal epithelium following excimer laser photorefractive keratectomy for the correction of myopia. Because the lesions were located centrally, possibly reducing visual acuity, the epithelium was removed mechanically.
Dot-like changes recurred in the same areas 4 weeks after epithelial debridement. Best spectacle-corrected visual acuity improved from 20/200 to 20/100 and remained stable thereafter.
Photorefractive keratectomy can lead to abnormal regeneration of epithelium basement membrane, possibly resulting in dot-like changes of corneal epithelium.
据报道,角膜地图样-点状-指纹状上皮改变是由外伤或手术操作(如放射状角膜切开术)引起的。
我们描述了1例准分子激光屈光性角膜切削术矫正近视后角膜上皮出现点状改变的病例。由于病变位于中央,可能会降低视力,因此机械性去除上皮。
上皮清创术后4周,相同区域再次出现点状改变。最佳矫正视力从20/200提高到20/100,此后保持稳定。
屈光性角膜切削术可导致上皮基底膜异常再生,可能导致角膜上皮点状改变。