Tsunoda S, Kurokawa S, Sakaki T, Yabuno T, Tsuzuki T, Kawaguchi S, Kiriishi R, Morimoto T
Department of Neurosurgery, Nara Medical University, Japan.
Neurol Med Chir (Tokyo). 1994 Jun;34(6):375-8. doi: 10.2176/nmc.34.375.
An 11-year-old boy presented with medulloblastoma occurring in the cerebellar vermis. Computed tomography and magnetic resonance imaging revealed numerous cysts and calcifications in the tumor. The tumor was subtotally removed and cellular synchronization radiation therapy given. He was discharged without neurological deficits. Histological examination showed the cysts represented necrotic foci. Macrophages, which appeared around the necrotic foci, were important in the development of the calcifications via proliferation of collagen fibers.
一名11岁男孩被诊断患有发生于小脑蚓部的髓母细胞瘤。计算机断层扫描和磁共振成像显示肿瘤内有大量囊肿和钙化。肿瘤次全切除并给予细胞同步放射治疗。他出院时无神经功能缺损。组织学检查显示囊肿为坏死灶。出现在坏死灶周围的巨噬细胞通过胶原纤维增殖在钙化形成过程中起重要作用。