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母血清筛查

Maternal serum screening.

作者信息

Carroll J C

机构信息

Department of Family and Community Medicine, University of Toronto.

出版信息

Can Fam Physician. 1994 Oct;40:1756-64.

PMID:7524838
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2380361/
Abstract

Maternal serum screening (MSS) measures three serum markers: alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol, from which the risk of fetal Down syndrome or open neural tube defect is calculated. Initially, 8% of women will have positive results. I present a protocol for investigating these women. Family physicians should be informed about MSS so they can give their patients information and guidance.

摘要

母血清筛查(MSS)检测三种血清标志物:甲胎蛋白、人绒毛膜促性腺激素和未结合雌三醇,据此计算胎儿患唐氏综合征或开放性神经管缺陷的风险。最初,8%的女性会有阳性结果。我提出了一个针对这些女性的调查方案。家庭医生应了解母血清筛查,以便他们能够为患者提供信息和指导。

相似文献

1
Maternal serum screening.母血清筛查
Can Fam Physician. 1994 Oct;40:1756-64.
2
Prenatal screening using maternal serum alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol: two-year experience in a health maintenance organization.使用母体血清甲胎蛋白、人绒毛膜促性腺激素和未结合雌三醇进行产前筛查:在一家健康维护组织中的两年经验。
J Matern Fetal Med. 1996 Mar-Apr;5(2):70-3. doi: 10.1002/(SICI)1520-6661(199603/04)5:2<70::AID-MFM4>3.0.CO;2-N.
3
A prospective evaluation of a second-trimester screening test for fetal Down syndrome using maternal serum alpha-fetoprotein, hCG, and unconjugated estriol.一项使用孕妇血清甲胎蛋白、人绒毛膜促性腺激素和未结合雌三醇对孕中期胎儿唐氏综合征进行筛查试验的前瞻性评估。
Obstet Gynecol. 1993 Jan;81(1):72-7.
4
[Maternal serum screening for Down syndrome and neural tube defects].[孕母血清唐氏综合征和神经管缺陷筛查]
Ned Tijdschr Geneeskd. 1998 Feb 21;142(8):409-15.
5
[Maternal serum screening for detection of fetal chromosome abnormalities].
Gynakologe. 1995 Oct;28(5):280-8.
6
Triploidy identified through second-trimester serum screening.通过孕中期血清筛查发现的三倍体。
Prenat Diagn. 2005 Mar;25(3):229-33. doi: 10.1002/pd.1115.
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Maternal serum screening for neural tube defects and fetal chromosome abnormalities.孕妇血清筛查神经管缺陷和胎儿染色体异常。
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Down syndrome: prenatal risk assessment and diagnosis.唐氏综合征:产前风险评估与诊断
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Periodic health examination, 1996 update: 1. Prenatal screening for and diagnosis of Down syndrome. Canadian Task Force on the Periodic Health Examination.定期健康检查,1996年更新版:1. 唐氏综合征的产前筛查与诊断。加拿大定期健康检查特别工作组。
CMAJ. 1996 Feb 15;154(4):465-79.

引用本文的文献

1
Assessment of the Effectiveness of Genetic Counseling by Telephone Compared to a Clinic Visit.电话遗传咨询与门诊就诊遗传咨询效果的评估
J Genet Couns. 2003 Apr;12(2):171-84. doi: 10.1023/A:1022663324006.
2
Family physicians in maternity care. Still in the game? Report from the CFPC's Janus Project.从事产科护理的家庭医生。还在这个领域吗?加拿大家庭医生学会贾纳斯项目的报告
Can Fam Physician. 2000 Mar;46:601-6, 609-11.
3
Ethics of maternal serum screening.母血清筛查的伦理学
Can Fam Physician. 1994 Dec;40:2064.

本文引用的文献

1
Differences in the acute and chronic antihypertensive effects of lisinopril and enalapril assessed by ambulatory blood pressure monitoring.通过动态血压监测评估赖诺普利和依那普利的急性和慢性降压作用差异。
Clin Exp Hypertens. 1993 Jan;15(1):71-89. doi: 10.3109/10641969309041612.
2
Age-specific detection and false-positive rates: an aid to counseling in Down syndrome risk screening.
Obstet Gynecol. 1993 Mar;81(3):447-50.
3
An association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities.孕妇血清甲胎蛋白水平低与胎儿染色体异常之间的关联。
Am J Obstet Gynecol. 1984 Apr 1;148(7):886-94. doi: 10.1016/0002-9378(84)90530-1.
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Assessment of the antihypertensive effect of lisinopril using 24-hour ambulatory monitoring.使用24小时动态监测评估赖诺普利的降压效果。
J Hum Hypertens. 1989 Jun;3 Suppl 1:11-5.
5
Maternal serum screening for Down's syndrome in early pregnancy.孕早期唐氏综合征的母体血清筛查。
BMJ. 1988 Oct 8;297(6653):883-7. doi: 10.1136/bmj.297.6653.883.
6
Maternal serum alpha-fetoprotein screening: report of a Canadian pilot project.孕妇血清甲胎蛋白筛查:加拿大试点项目报告。
CMAJ. 1987 Aug 15;137(4):285-93.
7
Screening for fetal Down's syndrome in pregnancy by measuring maternal serum alpha-fetoprotein levels.通过检测孕妇血清甲胎蛋白水平来筛查胎儿唐氏综合征。
N Engl J Med. 1987 Aug 6;317(6):342-6. doi: 10.1056/NEJM198708063170603.
8
Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alpha-fetoprotein level.利用女性年龄和血清甲胎蛋白水平估算其怀有唐氏综合征相关妊娠的风险。
Br J Obstet Gynaecol. 1987 May;94(5):387-402. doi: 10.1111/j.1471-0528.1987.tb03115.x.
9
Prenatal testing for maternal serum alpha-fetoprotein.
Am Fam Physician. 1987 Apr;35(4):169-74.
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Lisinopril and enalapril in hypertension: a comparative study using ambulatory monitoring.
J Hum Hypertens. 1990 Jun;4(3):235-9.