Effects of lindane exposure on rainbow trout (Oncorhynchus mykiss) immunity. I. Effect of lindane on antibody-secreting cells (ASC) measured by ELISPOT assay.
作者信息
Dunier M, Siwicki A K
机构信息
Laboratoire de Toxicologie Metabolique et Ecotoxicologie, INRA-ENVL, Marcy l'Etoile, France.
出版信息
Ecotoxicol Environ Saf. 1994 Feb;27(1):1-6. doi: 10.1006/eesa.1994.1001.
PMID:7525199
Abstract
Yersinia ruckeri vaccine was injected in rainbow trout 7 days after ip contamination with 10, 50, or 100 mg lindane per kilogram body weight. The antibody-secreting cells measured by ELISPOT assay were affected by the insecticide, slightly for 10 mg and strongly for higher concentrations. Consequently the antibody production in sera, measured by agglutination, was suppressed.
摘要
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