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The pathophysiologic role of alpha 4 integrins in vivo.

作者信息

Lobb R R, Hemler M E

机构信息

Biogen, Inc., Cambridge, Massachusetts 02142.

出版信息

J Clin Invest. 1994 Nov;94(5):1722-8. doi: 10.1172/JCI117519.

DOI:10.1172/JCI117519
PMID:7525645
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC294562/
Abstract
摘要

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The pathophysiologic role of alpha 4 integrins in vivo.α4整合素在体内的病理生理作用。
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本文引用的文献

1
The efficacy of LFA-1 and VLA-4 antibody treatment in rat vascularized cardiac allograft rejection.
Transplantation. 1993 May;55(5):1196-9.
2
Endothelial-leukocyte adhesion molecules.内皮细胞-白细胞黏附分子
Annu Rev Immunol. 1993;11:767-804. doi: 10.1146/annurev.iy.11.040193.004003.
3
Alpha 4/180, a novel form of the integrin alpha 4 subunit.α4/180，整合素α4亚基的一种新型形式。
J Biol Chem. 1993 Apr 5;268(10):7028-35.
4
Monoclonal antibodies to the integrin alpha-4 subunit inhibit the murine contact hypersensitivity response.针对整合素α-4亚基的单克隆抗体可抑制小鼠接触性超敏反应。
Eur J Immunol. 1993 Mar;23(3):682-8. doi: 10.1002/eji.1830230317.
5
Adhesion to fibronectin prolongs eosinophil survival.与纤连蛋白的黏附作用可延长嗜酸性粒细胞的存活时间。
J Exp Med. 1993 Mar 1;177(3):839-43. doi: 10.1084/jem.177.3.839.
6
Antigen-independent processes in antigen-specific immunity. A role for alpha 4 integrin.抗原特异性免疫中的抗原非依赖过程。α4整合素的作用。
J Immunol. 1993 Feb 15;150(4):1172-82.
7
Expression of a protective intestinal immune response can be inhibited at three distinct sites by treatment with anti-alpha 4 integrin.用抗α4整合素进行治疗可在三个不同位点抑制保护性肠道免疫反应的表达。
J Immunol. 1993 Nov 1;151(9):4790-802.
8
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo.一种识别极晚期活化抗原-4的单克隆抗体可在体内抑制嗜酸性粒细胞聚集。
J Exp Med. 1993 Feb 1;177(2):561-6. doi: 10.1084/jem.177.2.561.
9
Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle.整合素α9亚基的序列和组织分布，β1的一种新型伴侣，广泛分布于上皮和肌肉中。
J Cell Biol. 1993 Dec;123(5):1289-97. doi: 10.1083/jcb.123.5.1289.
10
Dual inhibition of VLA-4 and LFA-1 maximally inhibits cutaneous delayed-type hypersensitivity-induced inflammation.VLA - 4和LFA - 1的双重抑制可最大程度地抑制皮肤迟发型超敏反应诱导的炎症。
Am J Pathol. 1993 Nov;143(5):1286-93.