Stippig S, Stelter W J, Messmer K
Chir Forum Exp Klin Forsch. 1978(1978):123-6.
Metabolic acidosis is a characteristic feature of SNP-induced hypotension; this acidosis is of hepatic origin and is not due to underperfusion of the organ but to cyanide-induced anaerobic metabolism. For SNP doses higher than 3 mg/kg body weight, lactate is produced in the myocardium, brain, and skeletal muscles. The observed changes were reversible after hypotension of 20 min duration.
代谢性酸中毒是硝普钠诱导的低血压的一个特征；这种酸中毒源于肝脏，并非由于器官灌注不足，而是由于氰化物诱导的无氧代谢。对于剂量高于3毫克/千克体重的硝普钠，心肌、大脑和骨骼肌会产生乳酸。在持续20分钟的低血压发作后，观察到的这些变化是可逆的。
