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[肠梗阻时肠壁的能量代谢]

[Energy metabolism of the intestinal wall in ileus].

作者信息

Uekermann U, Schorn B, Isselhard W

出版信息

Chir Forum Exp Klin Forsch. 1978(1978):41-5.

PMID:752604
Abstract

In dogs, a segment of an aborrally occluded small intestine was anastomosed to the right colic flexure; thus, distal to the trapping ileocecal valve a local intestinal obstruction developed within a week in the small and large intestines, which locally stimulates the ileus situtation in man. Distrubances of the energy metabolism, as demonstrated by significant changes in the adenylic acid and phosphocreatine system, were more intensive in the mucosal layers of the small intestine than in those of the large intestine, whereas the smooth muscle layers were unaffected. The results reflect different disturbances of blood flow, energy needs, and adaptability of intestinal mucosa and musculature.

摘要

在犬中,将一段向口端闭塞的小肠与右结肠曲进行吻合;因此,在一周内,在回盲瓣受阻的远侧,小肠和大肠内出现了局部肠梗阻,这在局部刺激了人类的肠梗阻情况。能量代谢紊乱,如腺苷酸和磷酸肌酸系统的显著变化所示,在小肠黏膜层比在大肠黏膜层更为强烈,而平滑肌层未受影响。结果反映了血流、能量需求以及肠黏膜和肌肉组织适应性的不同紊乱情况。

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