Kojima Y, Kuwana N, Noji M, Tosa J
Department of Neurosurgery, Yokohama Minami Kyosai Hospital.
Neurol Med Chir (Tokyo). 1994 Sep;34(9):588-92. doi: 10.2176/nmc.34.588.
The use of superdelayed thallium-201 single photon emission computed tomography (201Tl SPECT) for differentiating malignant gliomas from cerebral metastases was investigated in 23 patients (7 with meningioma, 6 with glioma, 7 with cerebral metastasis, 1 with each of neurinoma, abscess, and necrosis). 4 mCi of 201Tl was injected intravenously, and gamma camera scans were performed after 10 minutes and 4, 24, 72, and 96 hours (superdelayed scan). The mean thallium index of meningiomas was significantly higher than those of gliomas and cerebral metastases after 10 minutes, while the mean thallium indices of meningiomas and gliomas were significantly higher than those of cerebral metastases after 96 hours. The combination of early and superdelayed 201Tl SPECT may be useful in differentiating malignant gliomas from cerebral metastases.
对23例患者（7例脑膜瘤、6例胶质瘤、7例脑转移瘤、1例神经鞘瘤、1例脓肿和1例坏死）进行了研究，以探讨使用超延迟铊-201单光子发射计算机断层扫描（201Tl SPECT）区分恶性胶质瘤和脑转移瘤。静脉注射4毫居里的201Tl，并在10分钟以及4、24、72和96小时后进行γ相机扫描（超延迟扫描）。10分钟后，脑膜瘤的平均铊指数显著高于胶质瘤和脑转移瘤，而96小时后，脑膜瘤和胶质瘤的平均铊指数显著高于脑转移瘤。早期和超延迟201Tl SPECT相结合可能有助于区分恶性胶质瘤和脑转移瘤。
