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星形胶质细胞组胺-钠共转运的机制与功能

Mechanism and function of histamine-sodium cotransport by astroglial cells.

作者信息

Huszti Z

机构信息

Department of Pharmacodynamics, Semmelweis University of Medicine, Budapest, Hungary.

出版信息

Agents Actions. 1994 Jun;41 Spec No:C58-9. doi: 10.1007/BF02007766.

DOI:10.1007/BF02007766
PMID:7526661
Abstract

There is a saturable and high affinity uptake system for histamine in astroglial cells. The uptake is metabolically driven, sodium dependent and electrogenic. We consider the functional significance of these findings.

摘要

星形胶质细胞中存在一种对组胺具有饱和性和高亲和力的摄取系统。该摄取过程由代谢驱动，依赖钠离子且具有电活性。我们探讨了这些发现的功能意义。

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Mechanism and function of histamine-sodium cotransport by astroglial cells.星形胶质细胞组胺-钠共转运的机制与功能
Agents Actions. 1994 Jun;41 Spec No:C58-9. doi: 10.1007/BF02007766.
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引用本文的文献

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Histamine (re)uptake by astrocytes: an experimental and computational study.星形胶质细胞摄取组胺：一项实验和计算研究。
J Mol Model. 2010 Jun;16(6):1151-8. doi: 10.1007/s00894-009-0624-9. Epub 2009 Dec 15.
2
Histamine-sensitive 86Rb transport in cultured type-2 astrocytes of rat brain.
Inflamm Res. 1995 Apr;44 Suppl 1:S46-7. doi: 10.1007/BF01674389.

本文引用的文献

1
[3H]histamine uptake and release by astrocytes from rat brain: effects of sodium deprivation, high potassium, and potassium channel blockers.
Neurochem Res. 1994 Oct;19(10):1249-56. doi: 10.1007/BF01006814.
2
Uptake, metabolism, and release of [3H]-histamine by glial cells in primary cultures of chicken cerebral hemispheres.
Glia. 1990;3(3):159-68. doi: 10.1002/glia.440030303.
3
In vitro formation of type 2 astrocytes derived from postnatal rat hypothalamus or cerebral cortex.源自新生大鼠下丘脑或大脑皮层的2型星形胶质细胞的体外形成。
Neuroscience. 1991;43(1):211-21. doi: 10.1016/0306-4522(91)90428-q.