Contralateral rotations induced by intrastriatal injections of agonists of excitatory amino acid receptors.
作者信息
Ossowska K, Wolfarth S
机构信息
Department of Neuro-Psychopharmacology, Polish Academy of Sciences, Kraków.
出版信息
Pol J Pharmacol. 1994 Jan-Apr;46(1-2):71-4.
PMID:7526935
Abstract
NMDA (100, 250 and 500 ng/0.5 microliters), kainic acid (50 and 100 ng/0.5 microliters) and AMPA (500 and 1000 ng/0.5 microliters), injected unilaterally into the ventrolateral part of the intermediate region of the caudate-putamen of rats, induced contralateral rotations. It is proposed that stimulation of NMDA, kainate and AMPA receptors present on strionigral neurons evokes an "antiparkinsonian effect".
摘要
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