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乳腺癌手术后的四联药物细胞毒性化疗。

Four drug combination cytotoxic chemotherapy following surgery for breast cancer.

作者信息

Edelstyn G A, Bates I S, Brinkley D, MacRae K D, Spittle H, Wheeler T

出版信息

Recent Results Cancer Res. 1978;68:109-12. doi: 10.1007/978-3-642-81332-0_15.

DOI:10.1007/978-3-642-81332-0_15
PMID:752851
Abstract

A prospective randomized clinical trial of treatment with vincristine, cyclophosphamide, methotrexate and 5-fluorouracil after conventional curative treatment for stage II breast cancer is described. The results at 2 years are recorded together with details of toxicity. Future plans are discussed briefly.

摘要

本文描述了一项针对II期乳腺癌患者在接受常规根治性治疗后,使用长春新碱、环磷酰胺、甲氨蝶呤和5-氟尿嘧啶进行治疗的前瞻性随机临床试验。记录了2年时的结果以及毒性细节。并简要讨论了未来计划。

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Chemotherapy of advanced breast cancer: a randomized trial of vincristine, Adriamycin, and cyclophosphamide (VAC) versus cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP).晚期乳腺癌的化疗:长春新碱、阿霉素和环磷酰胺(VAC)与环磷酰胺、甲氨蝶呤、5-氟尿嘧啶和泼尼松(CMFP)的随机试验。
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