[Clinical analysis of 126 cases with NHL in extra-node of head and neck patients in stage I and II].

UNLABELLED

From 1987.1.1. to 1990. 12. 31. 126 cases of extranode untreated non-Hodgkin's lymphoma (NHL) in I-II stage were analysed. All of the 126 cases had proved by pathology. The sites of primary disease were oral-pharynx in 64.3%, nasal cavity in 31% and others in 4.7%. The age of patients was between 5-69 (30-60 in 62.7%). According to the international working dassification, there was 1 case of low grade, 48 (38%) of intermediate and 77(61%) of high grade. According to Ann Arbor clinical staging, there were 33 cases of stage I and 93 cases of stage II. According to the pathological grades and clinical stages, the treatment was divided into 4 groups. (1) CT-RT 63 cases, (2) RT-CT 26 cases, (3) RT 32 cases and (4) CT 5 cases. After treatment, CR were obtained in 101 cases, PR 18 cases and P 3 cases, CR+PR were 97.5%. The 1,2,3,4,5 years survival rates of the 126 cases were 83.3% (105/126), 70.6% (89/126), 68.2% (60/88), 62.2% (46/74), 58.3% (21/36), respectively.

CONCLUSION

(1) The pathological grades were not closely related to the survival rate of patients. (2) The comparison of clinical stages I:II showed a P value < 0.05. (3) The comparison of survival rates of CR:PR:P showed a P value < 0.05 and < 0.001, respectively. (4) There was no statistically significant difference in the four treatment protocols. But the multitherapy group was better. (5) Before the RT, four cycles of CT showed a better result than that of 1-3 cycles.