Quaranta M, Cohen S Y, Krott R, Sterkers M, Soubrane G, Coscas G J
Department of Ophthalmology, Höpital Intercommunal, Créteil, France.
Am J Ophthalmol. 1995 Feb;119(2):136-42. doi: 10.1016/s0002-9394(14)73865-6.
The fluorescein angiographic features of angioid streaks are variable, and angioid streaks and their main complication, choroidal neovascularization, can sometimes be difficult to visualize in the presence of diffuse pigment migration, diffuse atrophy of the retinal pigment epithelium, or hemorrhage. The objective of the present investigation was to define the indocyanine green angiographic features of angioid streaks and to compare them with findings on fluorescein angiography.
For this prospective study, we recruited 22 consecutive patients, 21 of whom had angioid streaks and one who had typical peau d'orange appearance of the fundus. Complete ophthalmologic examination, fluorescein angiography, and indocyanine green videoangiography by the means of scanning laser ophthalmoscope were performed on all patients.
In 21 patients with angioid streaks and in one patient with peau d'orange appearance of the fundus, indocyanine green videoangiography showed angioid streaks in the form of hyperfluorescent lines with numerous associated hyperfluorescent foci. The angioid streaks were more clearly visualized and were seen to be more numerous and larger by indocyanine green videoangiography than with red-free images or fluorescein angiography. Choroidal neovascularization was suspected in six eyes but could be precisely localized by fluorescein angiography in only three eyes. Indocyanine green angiography allowed precise localization of choroidal neovascularization in all six of these eyes.
These findings indicate that indocyanine green videoangiography provides different information than fluorescein angiography in the evaluation of angioid streaks and can more precisely localize their neovascular complications.
血管样条纹的荧光素血管造影特征多变，在存在弥漫性色素迁移、视网膜色素上皮弥漫性萎缩或出血时，血管样条纹及其主要并发症脉络膜新生血管有时难以看清。本研究的目的是明确血管样条纹的吲哚菁绿血管造影特征，并将其与荧光素血管造影的结果进行比较。
在这项前瞻性研究中，我们连续招募了22例患者，其中21例有血管样条纹，1例眼底有典型的橘皮样外观。对所有患者进行了全面的眼科检查、荧光素血管造影以及使用扫描激光检眼镜进行吲哚菁绿视频血管造影。
在21例有血管样条纹的患者和1例眼底有橘皮样外观的患者中，吲哚菁绿视频血管造影显示血管样条纹为高荧光线条，伴有许多相关的高荧光灶。与无赤光图像或荧光素血管造影相比，吲哚菁绿视频血管造影能更清晰地显示血管样条纹，且显示出的血管样条纹数量更多、更大。6只眼中怀疑有脉络膜新生血管，但荧光素血管造影仅在3只眼中能准确定位。吲哚菁绿血管造影能在所有这6只眼中准确地定位脉络膜新生血管。
这些发现表明，在评估血管样条纹时，吲哚菁绿视频血管造影提供了与荧光素血管造影不同的信息，并且能更精确地定位其新生血管并发症。
