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体外培养的杀鱼巴斯德氏菌表达的荚膜多糖。

Capsular polysaccharide expressed by Pasteurella piscicida grown in vitro.

作者信息

Bonet R, Magariños B, Romalde J L, Simon-Pujol M D, Toranzo A E, Congregado F

机构信息

Department de Microbiologia i Parasitologia Sanitàries, Facultat de Farmàcia, Universitat de Barcelona, Spain.

出版信息

FEMS Microbiol Lett. 1994 Dec 15;124(3):285-9. doi: 10.1111/j.1574-6968.1994.tb07298.x.

DOI:10.1111/j.1574-6968.1994.tb07298.x
PMID:7531663
Abstract

Pasteurella piscicida grown in a glucose-rich medium produces a capsule that can be see under light and electron microscopy. The capsular polysaccharide was purified and characterized by chemical and HPLC analysis. The polymer has the composition glucose/mannose/N-acetylgalactosamine/galacturonic acid/acetic acid in the molar ratios of approximately 2.5:1.3:0.5:0.4:2.5. The polysaccharide was immunogenic in rabbits and did not cross-react with antibodies against the O-antigen lipopolysaccharide.

摘要

在富含葡萄糖的培养基中生长的杀鱼巴斯德菌会产生一种在光学显微镜和电子显微镜下都可见的荚膜。对荚膜多糖进行了纯化,并通过化学分析和高效液相色谱分析对其进行了表征。该聚合物的组成是葡萄糖/甘露糖/N-乙酰半乳糖胺/半乳糖醛酸/乙酸,摩尔比约为2.5:1.3:0.5:0.4:2.5。该多糖对兔子具有免疫原性,且不与抗O抗原脂多糖的抗体发生交叉反应。

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