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黑色素瘤患者免疫状态的研究:卡介苗免疫治疗前后淋巴细胞转化试验和白细胞游走抑制试验中皮内和表皮试验的细胞介导免疫反应(作者译)

[Studies on the immune status of melanoma patients: cell-mediated immune reactions in intracutaneous and epicutaneous tests in the lymphocyte transformation test and the leukocyte-migration inhibition test before and during BCG immunotherapy (author's transl)].

作者信息

Knopf B, Wätzig V, Knöll B

出版信息

Arch Geschwulstforsch. 1978;48(8):722-8.

PMID:753194
Abstract

Active immunotherapy with BCG was carried out postoperatively in 22 patients with malignant melanoma. At the beginning and 6 months after treatment cell-mediated immune reactions were checked by both in vivo tests (intracutaneous test with tuberculin and patchtest with DNCB) and in vitro tests (lymphocyte stimulation and leukocyte migration inhibition with tuberculin and DNCB). The results have shown that stimulation of immune response may be obtained by systemic BCG therapy.

摘要

对22例恶性黑色素瘤患者术后进行了卡介苗主动免疫治疗。在治疗开始时及治疗后6个月,通过体内试验(结核菌素皮内试验和二硝基氯苯斑贴试验)和体外试验(淋巴细胞刺激试验以及结核菌素和二硝基氯苯所致的白细胞游走抑制试验)检查细胞介导的免疫反应。结果表明,全身卡介苗治疗可激发免疫反应。

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