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本文引用的文献

1
VEGF/VPF: the angiogenesis factor found?血管内皮生长因子/血管通透因子:已发现的血管生成因子?
Curr Biol. 1993 Oct 1;3(10):699-702. doi: 10.1016/0960-9822(93)90073-w.
2
Apoplexy associated with brain tumours.与脑肿瘤相关的中风
Can Med Assoc J. 1961 Feb 11;84(6):303-5.
3
The endothelial hyperplasia of the cerebral blood vessels with brain tumors, and its sarcomatous transformation.脑肿瘤伴发的脑血管内皮增生及其肉瘤样变。
Cancer. 1958 Mar-Apr;11(2):264-77. doi: 10.1002/1097-0142(195803/04)11:2<264::aid-cncr2820110207>3.0.co;2-d.
4
Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors.人脑肿瘤中92,000分子量IV型胶原酶水平升高。
Cancer Res. 1993 May 15;53(10 Suppl):2208-11.
5
Transforming growth factor-beta in neural embryogenesis and neoplasia.转化生长因子-β在神经胚胎发生和肿瘤形成中的作用
Hum Pathol. 1993 May;24(5):457-62. doi: 10.1016/0046-8177(93)90156-b.
6
Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.血管通透性因子/血管内皮生长因子基因在中枢神经系统肿瘤中的表达。
J Clin Invest. 1993 Jan;91(1):153-9. doi: 10.1172/JCI116165.
7
Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism.血小板反应蛋白通过一种新机制导致内皮细胞分泌的潜伏转化生长因子-β激活。
J Cell Biol. 1993 Aug;122(4):923-32. doi: 10.1083/jcb.122.4.923.
8
The p53 gene and protein in human brain tumors.人脑肿瘤中的p53基因与蛋白
J Neuropathol Exp Neurol. 1994 Jan;53(1):11-21. doi: 10.1097/00005072-199401000-00002.
9
Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells.碱性成纤维细胞生长因子调节微血管内皮细胞中的整合素表达。
Mol Biol Cell. 1993 Oct;4(10):973-82. doi: 10.1091/mbc.4.10.973.
10
Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels.血管内皮生长因子和碱性成纤维细胞生长因子对胶原凝胶内牛毛细血管内皮细胞增殖和条索形成的协同作用。
Lab Invest. 1993 Nov;69(5):508-17.

神经胚胎发生和肿瘤形成中的血管生成生长因子。

Angiogenic growth factors in neural embryogenesis and neoplasia.

作者信息

Zagzag D

机构信息

Department of Pathology, Kaplan Comprehensive Cancer Center, New York University Medical Center, New York.

出版信息

Am J Pathol. 1995 Feb;146(2):293-309.

PMID:7531952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1869862/
Abstract

"Blood vessels have the power to increase within themselves which is according to the necessity whether natural or diseased. As a further proof that this is a general principle, we find that all growing parts are much more vascular than those that are come to their full growth; because growth is an operation beyond the simple support of the part. This is the reason why young animals are more vascular than those that are full grown. This is not peculiar to the natural operation of growth, but applies also to disease and restoration."

摘要

血管有根据自身需要(无论是自然的还是患病的)进行自身扩张的能力。作为这是一个普遍原则的进一步证据,我们发现所有正在生长的部位比那些已经发育完全的部位血管丰富得多;因为生长是一种超越该部位简单维持的活动。这就是幼小动物比成年动物血管更丰富的原因。这并非生长的自然活动所特有,疾病和恢复过程也适用。