Mizuno M, Miyakawa K, Mizutani A, Furuse M
Auris Nasus Larynx. 1978;5(1):49-53. doi: 10.1016/s0385-8146(78)80006-6.
Pulmonary scintigraphy using 99mTc-MAA clearly demonstrated a perfusion defect in the entire left lung of an 11-month-old girl with endobronchial foreign body. Other initial examinations, including a chest roentgenogram, showed only minimal changes. Repeated pulmonary scintigraphy 24 hr after endoscopic removal of a peanut fragment from the left main stem bronchus demonstrated almost normal blood flow in the left lung. The well-known physiological explanation for diminished pulmonary blood flow due to endobronchial foreign bodies is as follows; alveolar hypoxia caused by hypoventilation due to bronchial check-valve obstruction leads to a pulmonary vasoconstriction with resultant diminution of the regional perfusion. Furthermore, the increase in alveolar pressure caused by bronchial check-valve obstruction may play a significant role in decreased pulmonary blood flow.
使用99mTc-MAA进行的肺闪烁扫描清楚地显示，一名患有支气管内异物的11个月大女孩的整个左肺存在灌注缺损。包括胸部X线片在内的其他初步检查仅显示出轻微变化。在内镜下从左主支气管取出花生碎片24小时后进行的重复肺闪烁扫描显示左肺血流几乎正常。支气管内异物导致肺血流减少的众所周知的生理学解释如下：由于支气管单向活瓣阻塞导致通气不足引起的肺泡缺氧会导致肺血管收缩，从而导致局部灌注减少。此外，支气管单向活瓣阻塞引起的肺泡压力升高可能在肺血流减少中起重要作用。
