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[中国类鼻疽的流行病学]

[Epidemiology of melioidosis in China].

作者信息

Li L, Lu Z, Han O

机构信息

Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences PLA, Beijing.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Oct;15(5):292-5.

PMID:7532109
Abstract

From 1975 to 1989, a total of 73 strains of P. pseudomallei was isolated from the water samples and the pathological samples of human and domestic animals in 13 counties and cities located different latitude from four provinces Qiong, Yue, Gui and Xiang in China. Serological investigation demonstrated that the geographical distribution of the organism had a significant correlation with the positive rate of antibodies against P. pseudomallei and the native foci of the organisms distributed over the southern subtropical zone and the edge of tropical zone in Qiong, Yue and Gui. In endemic areas, the positive rates of antibodies against P. pseudomallei in human-beings, horses, oxen and pigs are 3.8%-15.2%, 9.1%-18.4%, 6.6%-33.0% and 35% respectively. The investigation results showed the horses and mules infected by the organism would interfere with quarantine of the animals, meanwhile, the meat contaminated by the bacterium would endanger the public health. In Sept. and Oct. of 1989, three cases in Zhanjiang and Sanya of Hainan were reported, two cases died of acute melioidosis with septicemia, another case was the chronic leg ulcers. So, it was predicated that there could have some cases of melioidosis which were misdiagnosed or missed out.

摘要

1975年至1989年,从中国琼、粤、桂、湘四省不同纬度的13个县市的水样以及人和家畜的病理样本中,共分离出73株类鼻疽杆菌。血清学调查表明,该菌的地理分布与抗类鼻疽杆菌抗体阳性率以及该菌在琼、粤、桂南部亚热带地区和热带边缘的自然疫源地显著相关。在流行地区,人、马、牛和猪的抗类鼻疽杆菌抗体阳性率分别为3.8% - 15.2%、9.1% - 18.4%、6.6% - 33.0%和35%。调查结果显示,感染该菌的马和骡会干扰动物检疫,同时,被该菌污染的肉类会危害公众健康。1989年9月和10月,海南湛江和三亚报告了3例病例,2例死于伴有败血症的急性类鼻疽病,另1例为慢性腿部溃疡。因此,据推测可能存在一些被误诊或漏诊的类鼻疽病病例。

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