Shibata H
Department of Veterinary Anatomy, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan.
Neurosci Res. 1994 Oct;20(4):331-6. doi: 10.1016/0168-0102(94)90055-8.
The terminal distribution of projections from the retrosplenial area to the retrohippocampal region was examined in the rat with anterograde transport of biotinylated dextran amine. Projections from the retrosplenial granular area (RSG) to the retrohippocampal region terminate predominantly ipsilaterally in layers I, III, V and VI of the presubiculum, layers I and IV-VI of the parasubiculum, the molecular and pyramidal cell layers of the subiculum, and layers I, III, V and VI of the entorhinal area. On the other hand, projections from the retrosplenial agranular area (RSA) terminate predominantly ipsilaterally in layers I and III of the presubiculum and layers V and VI of the entorhinal and perirhinal areas, and ipsilaterally in layers IV-VI of the parasubiculum. The results show that projections from the RSG to the retrohippocampal region are as massive as those from the RSA, and that each retrosplenial area has distinct projection fields in the retrohippocampal region. This suggests that each retrosplenial area may play some distinct functional roles in memory and learning processes such as spatial behavioral learning.
利用生物素化葡聚糖胺的顺行运输法，在大鼠中研究了脾后区至海马后区域投射的终末分布。脾后颗粒区（RSG）至海马后区域的投射主要同侧终止于前下托的I、III、V和VI层、副下托的I层和IV-VI层、海马下托的分子层和锥体细胞层以及内嗅区的I、III、V和VI层。另一方面，脾后无颗粒区（RSA）的投射主要同侧终止于前下托的I和III层、内嗅区和嗅周区的V和VI层，以及同侧副下托的IV-VI层。结果表明，RSG至海马后区域的投射与RSA的投射一样密集，并且每个脾后区域在海马后区域具有不同的投射场。这表明每个脾后区域可能在记忆和学习过程（如空间行为学习）中发挥一些不同的功能作用。
