Lang A E, Curran T, Provias J, Bergeron C
Morton and Gloria Shulman Movement Disorder Center, Toronto Hospital, Ontario, Canada.
Can J Neurol Sci. 1994 Nov;21(4):311-8. doi: 10.1017/s0317167100040889.
We report three patients with striatonigral degeneration highlighting the correlation between magnetic resonance imaging (MRI) and the pathological changes. The "slit-like void signal" observed in the putamen is typical of striatonigral degeneration and can be used to assist diagnosis during life. Our histochemical studies support the concept that increased iron deposition in the putamen is responsible for this MRI picture.
我们报告了三例纹状体黑质变性患者，突出了磁共振成像（MRI）与病理变化之间的相关性。在壳核中观察到的“裂隙状空洞信号”是纹状体黑质变性的典型表现，可用于生前辅助诊断。我们的组织化学研究支持这样一种观点，即壳核中铁沉积增加是导致这种MRI表现的原因。
