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Expression of human DAF and MCP on pig endothelial cells protects from human complement.

作者信息

Carrington C A, Richards A C, Cozzi E, Langford G, Yannoutsos N, White D J

机构信息

Department of Surgery, University of Cambridge, UK.

出版信息

Transplant Proc. 1995 Feb;27(1):321-3.

PMID:7533398
Abstract
摘要

相似文献

1
Expression of human DAF and MCP on pig endothelial cells protects from human complement.
Transplant Proc. 1995 Feb;27(1):321-3.
2
Permanent expression of human CD59 and/or decay-accelerating factor by rat endothelial cells confers protection from human complement-mediated lysis.
Transplant Proc. 1995 Feb;27(1):336-7.
3
Effect of transfected MACIF (CD59) on complement-mediated swine endothelial cell lysis, compared with those of membrane cofactor protein (CD46) and decay-accelerating factor (CD55).与膜辅因子蛋白（CD46）和衰变加速因子（CD55）相比，转染的膜攻击复合物抑制因子（CD59）对补体介导的猪内皮细胞裂解的影响。
Transplant Proc. 1995 Feb;27(1):328-9.
4
Effect of transfectant molecules, MCP, DAF, and MCP/DAF hybrid on xenogeneic vascular endothelium.
Transplant Proc. 1994 Jun;26(3):1253-4.
5
High-level tissue specific expression of human CD59, MCP, and DAF proteins from genomic clones in transgenic mice.转基因小鼠中来自基因组克隆的人CD59、MCP和DAF蛋白的高水平组织特异性表达。
Transplant Proc. 1996 Apr;28(2):693.
6
Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAE hybrid, on complement-mediated swine endothelial cell lysis.转染的补体调节蛋白、膜辅助蛋白（MCP）、衰变加速因子（DAF）以及MCP/DAF杂合体对补体介导的猪内皮细胞裂解的影响。
Transplantation. 1994 Oct 15;58(7):834-40.
7
Endothelial expression of human decay accelerating factor in transgenic pig tissue: a potential approach for human complement inactivation in discordant xenografts.人衰变加速因子在转基因猪组织中的内皮表达：一种在异种移植中使人类补体失活的潜在方法。
Transplant Proc. 1995 Feb;27(1):326-7.
8
Evidence that double transfection to xenoendothelial cells using GPI-anchoring complement regulatory factor (decay-accelerating factor and homologous restriction factor 20) gene is useful for the inhibition of human complement-mediated cytolysis.
Transplant Proc. 1995 Feb;27(1):330.
9
Inhibition of species-specific complement-mediated cytolysis in xenoendothelial cells transfected with GPI-anchored complement regulatory factor (DAF, HRF20) gene using retroviral vector: comparison between single (DAF or HRF20) and double (DAF and HRF20) transfected xenoendothelial cells.
Transplant Proc. 1994 Jun;26(3):1243-4.
10
Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter.由猪MCP基因启动子调控表达人衰变加速因子的转基因猪。
Mol Reprod Dev. 2002 Mar;61(3):302-11. doi: 10.1002/mrd.10043.

引用本文的文献

1
Production of multiple transgenic Yucatan miniature pigs expressing human complement regulatory factors, human CD55, CD59, and H-transferase genes.生产表达人补体调控因子、人 CD55、CD59 和 H-转移酶基因的多个转基因尤卡坦微型猪。
PLoS One. 2013 May 21;8(5):e63241. doi: 10.1371/journal.pone.0063241. Print 2013.
2
Reduced sensitivity to human serum inactivation of enveloped viruses produced by pig cells transgenic for human CD55 or deficient for the galactosyl-alpha(1-3) galactosyl epitope.对由转人CD55基因的猪细胞或缺乏α（1-3）半乳糖基表位的猪细胞产生的包膜病毒的人血清灭活敏感性降低。
J Virol. 2004 Jun;78(11):5812-9. doi: 10.1128/JVI.78.11.5812-5819.2004.
3
Engineering of recombinant soluble CD46: an inhibitor of complement activation.
重组可溶性CD46的工程改造：一种补体激活抑制剂。
Immunology. 1996 Mar;87(3):348-54.