Aughsteen A A, Kataoka K
Department of Anatomy, Hiroshima University School of Medicine, Japan.
Hiroshima J Med Sci. 1994 Dec;43(4):115-8.
An immunohistochemical localization of amylase was demonstrated in human pancreatic acinar cells using a commercial anti-human pancreatic amylase antibody. The immunofluorescence was mainly localized in the cell apices, and some differences in the intensity of the fluorescence was observed among the acinar cells in respect to their location from the islets of Langerhans. The peri-insular acinar cells showed a brighter fluorescence than the cells of tele-insular acini. This inhomogeneity of pancreatic amylase distribution in the human exocrine pancreas adds a further clue to the concept of insulo-acinar interaction.
使用市售抗人胰腺淀粉酶抗体，在人胰腺腺泡细胞中证实了淀粉酶的免疫组织化学定位。免疫荧光主要定位于细胞顶端，并且观察到腺泡细胞中荧光强度在距胰岛的位置方面存在一些差异。胰岛周围的腺泡细胞比远胰岛腺泡的细胞显示出更亮的荧光。人外分泌胰腺中胰腺淀粉酶分布的这种不均匀性为胰岛 - 腺泡相互作用的概念提供了进一步的线索。
