通过高效液相色谱法改进内分泌诊断。
An improvement of the endocrine diagnosis by high-performance liquid chromatography.
作者信息
Stefănescu A M
机构信息
C. I. Parhon Institute of Endocrinology, Bucharest, Romania.
出版信息
Rom J Endocrinol. 1993;31(3-4):165-70.
PMID:7535156
Abstract
The assessment of catecholamines (NE, E), essential metabolites (VMA, HVA) and serotonergic metabolite 5HIIA in urine by HPLC with UV detection is of interest for clinical diagnosis concerning HTA, pheochromocytoma, neuroblastoma, carcinoid syndrome, hypotension, etc. In the same urine sample one can detect (following preliminary steps) by HPLC the above--mentioned biochemical parameters with good reproducibility and sensitivity.
摘要
采用高效液相色谱法（HPLC）结合紫外检测法对尿液中的儿茶酚胺（去甲肾上腺素、肾上腺素）、重要代谢产物（香草扁桃酸、高香草酸）和血清素能代谢产物5-羟吲哚乙酸进行评估，对于高血压、嗜铬细胞瘤、神经母细胞瘤、类癌综合征、低血压等疾病的临床诊断具有重要意义。在同一份尿液样本中（经过初步处理后），通过高效液相色谱法可以检测上述生化参数，且具有良好的重现性和灵敏度。
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