Zhao L R, Zhao W X, Shao M H
First Affiliated Hospital of Jiamusi Medical College.
Zhonghua Fu Chan Ke Za Zhi. 1994 Oct;29(10):607-9, 638.
This paper reports fourteen cases of advanced and recurrent gynecologic cancers treated with prolonged arterial perfusion chemotherapy by catheterization of both internal iliac arteries through femoral arteriopuncture under X-ray. The immediate effective rate was 78.5%, follow-up rate 100%. By this technique anticancer drugs can be selectively injected into vessels supplying the tumors. The drug is concentrated within the tumor resulting in longterm better local effects, and fewer general side reactions, and a much higher dose than that which could be given conventionally. This technique is considered as a new route of treatment in gynecologic tumors.
本文报道了14例晚期及复发性妇科癌症患者，通过在X线引导下经股动脉穿刺对双侧髂内动脉进行插管，实施长时间动脉灌注化疗。近期有效率为78.5%，随访率为100%。通过该技术，抗癌药物能够选择性地注入肿瘤供血血管。药物在肿瘤内聚集，从而产生更好的长期局部疗效，全身副作用更少，且剂量比传统给药方式高得多。该技术被认为是妇科肿瘤治疗的一种新途径。
