Preisman R A, Halpern S
Eur J Nucl Med. 1978;3(1):69-70. doi: 10.1007/BF00253481.
A patient with thyroid cancer is described whose metastases were detected only after the administration of a large therapeutic dose of 131 Iodine. This suggests that very high doses of 131 Iodine might permit diagnoses of metastatic lesions not otherwise detected. This phenomenon may be explained by the improved counting statistics which occur with the use of a higher dose of the isotope. In such cases, exceedingly high doses of 131 Iodine might be necessary for successful tumor ablation.
本文描述了一名甲状腺癌患者，其转移灶仅在给予大剂量治疗性 131 碘后才被发现。这表明，非常高剂量的 131 碘可能有助于诊断其他方法无法检测到的转移病灶。这种现象可以用使用更高剂量同位素时计数统计的改善来解释。在这种情况下，可能需要极高剂量的 131 碘才能成功消融肿瘤。
