Nozdrachev A D, Flerov M A, Stepanova T P, Tolstukhina T I
Fiziol Zh Im I M Sechenova. 1994 Sep;80(9):22-8.
The study has shown seasonal changes in the responses of the frog bladder isolated preparation to exogenous adrenalin. The finding is explained by heterogeneity of the smooth muscle adrenoreceptors and alteration of functionally domineering populations during the winter-spring cycle. The changes corresponded to modifications of the fraction composition of phospholipids, the modifications being, probably, one of the ways of regulation of the smooth muscle adrenoreceptor apparatus' activity.
该研究表明，离体青蛙膀胱制备物对外源肾上腺素的反应存在季节性变化。这一发现可通过平滑肌肾上腺素能受体的异质性以及冬春周期中功能主导群体的变化来解释。这些变化与磷脂组分组成的改变相对应，这种改变可能是调节平滑肌肾上腺素能受体装置活性的方式之一。
