Lucci S, Raschellà G F, Marzullo A, Rivolta R, Mascagni D, Di Matteo F M, Peparini N
Università degli Studi La Sapienza, Roma.
G Chir. 1994 Nov-Dec;15(11-12):481-91.
Preliminary results of a prospective study on sialomucin content found either at resection margins of colo-rectal cancer after curative surgery or in endoscopic biopsy specimens of colonic mucosa in thirteen patients selected for the follow up are reported. Though not statistically significant because of the small number of cases enrolled, preliminary data indicate that clinical application of differential mucin staining in colo-rectal neoplasms is potentially useful to predict subgroups of patients at risk for local recurrence as well as metachronous colo-rectal cancers.
报告了一项前瞻性研究的初步结果，该研究针对13例被选入随访的患者，检测了其根治性手术后结直肠癌切除边缘或结肠黏膜内镜活检标本中的涎黏蛋白含量。尽管由于纳入病例数较少，结果无统计学意义，但初步数据表明，结直肠肿瘤中黏蛋白差异染色的临床应用可能有助于预测有局部复发及异时性结直肠癌风险的患者亚组。
