[异位妊娠：治疗方法的选择标准]

[Ectopic pregnancy: criteria to choose therapy].

作者信息

Darai E, Sitbon D, Benifla J L, Deval B, Guglielmina J N, Filippini F, Créquat J, Madelenat P

机构信息

Hôpital Bichat, Service de gynécologie-obstétrique, Paris.

出版信息

Contracept Fertil Sex. 1995 Mar;23(3):192-8.

PMID:7537151

Abstract

The ectopic pregnancy (EP) could be treated by spontaneous resolution, or medical treatment or laparoscopic treatment. Spontaneous resolution of EP with beta hCG < 1,000 mUl/ml, plasmatic progesterone < 5 ng/ml had 74% success rate. Methotrexate (MTX) injection is the common Medical treatment of EP with beta hCG < or = 5,000 mUl/ml and mean diameter of EP < or = 3 cm: a single dose of 50 mg/m2 or 1 mg/kg intramuscular injection had 93.4% success rate; local injection under sonographic control (1 mg/kg) had 80.2% success rate. The surgical conservative treatment by laparoscopy had 94% success rate.

摘要

异位妊娠（EP）可通过自然消退、药物治疗或腹腔镜治疗。β-hCG＜1000mUl/ml且血浆孕酮＜5ng/ml的EP自然消退成功率为74%。甲氨蝶呤（MTX）注射是β-hCG≤5000mUl/ml且EP平均直径≤3cm的EP常见药物治疗方法：单次肌肉注射50mg/m²或1mg/kg的成功率为93.4%；超声引导下局部注射（1mg/kg）的成功率为80.2%。腹腔镜手术保守治疗的成功率为94%。