Timoşca G C, Cotuţiu C, Gavriliţà L
Clinique de Chirurgie Orale et Maxillo-Faciale, Université de Médecine et de Pharmacie, laşi, Roumanie.
Rev Stomatol Chir Maxillofac. 1995;96(2):88-95.
Five out of 4,172 operated maxillary cysts (3 developed within the maxillary and 2 in the mandible) presented a malignant change of epithelium. In all these 5 cases histology demonstrated a transition from normal to cancerous epithelium. The overall percentage of malignant change was of 0.12%, with 0.077% for non-keratinized epithelium lining odontogenic cysts (3 cases) and 0.65%, that is 8 times higher, for keratinized ones (2 cases). Keratinization of cystic epithelium and chronic inflammatory lesions were the main risk factors.
在4172例接受手术的上颌囊肿中，有5例（3例发生在上颌，2例发生在下颌）出现上皮恶性变。在所有这5例病例中，组织学显示上皮从正常转变为癌性。恶性变的总体百分比为0.12%，牙源性囊肿内衬的非角化上皮为0.077%（3例），角化上皮为0.65%，即高出8倍（2例）。囊性上皮的角化和慢性炎性病变是主要危险因素。
