Hofstädter F
Institut für Pathologie, Universität Regensburg.
Chirurg. 1995 Mar;66(3):174-81.
In this review the morphologically defined steps of wound healing are described. Then the mechanisms of molecular regulation are discussed, which are the basis of the phases of wound healing. A main topic is the role of signal peptides in the regulation of cellular and stromal alterations during wound healing. An overview is given about the respective growth factors, their main function during wound healing and their receptors. Finally, analogies with fetal wound healing and the therapeutic modulation of wound-healing disturbances are discussed.
在本综述中，描述了伤口愈合在形态学上明确的步骤。接着讨论了分子调控机制，这些机制是伤口愈合各阶段的基础。一个主要主题是信号肽在伤口愈合过程中对细胞和基质改变的调控作用。概述了各自的生长因子、它们在伤口愈合过程中的主要功能及其受体。最后，讨论了与胎儿伤口愈合的相似之处以及对伤口愈合障碍的治疗性调节。
