Hutson D G, Russell E, Levi J U, Livingstone A S, Yrizarry J M, Guerra J, Scagnelli T
University of Miami School of Medicine, Department of Surgery, FL 33101, USA.
Am Surg. 1995 Jun;61(6):518-20.
It is generally conceded that palliation for proximal bile duct tumors (Klatskin) is exceptional if obstruction and the resultant infections can be prevented. Our experience with balloon dilatations thru the subcutaneously placed afferent limb of a choledocho or hepatico jejunostomy in patients with benign strictures suggests that this approach will be effective in patients with malignancies and thus provide long-term control of the obstruction without the need for external tubes. This is a report on one patient who, following a resected Klatskin tumor with positive margins, was treated with transhepatic internal external stents and was converted to a subcutaneous limb following numerous bouts of cholangitis. A schedule for repeat dilatations thru the jejunal limb was established. The patient has remained afebrile with a normal bilirubin and a moderately elevated alkaline phosphatase. Recurrent tumors or postirradiation strictures in patients with resected Klatskin tumors can be effectively controlled by repeated balloon dilatation without the need for external stents.
一般认为,如果能够预防梗阻及由此引发的感染,近端胆管肿瘤(克氏肿瘤)的姑息治疗效果甚微。我们对患有良性狭窄的患者通过经皮下放置的胆总管或肝空肠吻合术的输入袢进行球囊扩张的经验表明,这种方法对恶性肿瘤患者也有效,从而无需外置导管即可长期控制梗阻。本文报告了1例患者,其克氏肿瘤切除术后切缘阳性,接受了经肝内外支架治疗,在经历多次胆管炎发作后改为皮下袢。制定了通过空肠袢进行重复扩张的计划。该患者一直无发热,胆红素正常,碱性磷酸酶中度升高。对于克氏肿瘤切除术后的复发性肿瘤或放疗后狭窄患者,通过重复球囊扩张无需外置支架即可有效控制。