银染核仁组成区嗜银蛋白在甲状腺滤泡性肿瘤细针穿刺涂片诊断中的作用。

Role of AgNOR in diagnosis of thyroid follicular neoplasms on fine-needle aspiration smears.

作者信息

Karmakar T, Dey P

机构信息

Department of Pathology and Cytology, PGIMER, Chandigarh, India.

出版信息

Diagn Cytopathol. 1995 Mar;12(2):148-9; discussion 149-51. doi: 10.1002/dc.2840120212.

DOI:10.1002/dc.2840120212

PMID:7539738

Abstract

This is a retrospective study to examine the role of AgNOR in differentiating thyroid follicular carcinoma and adenoma preoperatively on fine-needle aspiration (FNA) smears. Nineteen histopathology-proven cases of follicular adenoma and carcinoma were selected for this study. May-Grünwald-Giemsa-stained smears were destined and AgNOR staining technique was employed. Significant differences of AgNOR values were observed among follicular carcinoma versus adenoma (P < .05) and follicular carcinoma versus control cases (P < .01). Thereby the AgNOR technique may have some role in differentiating between benign and malignant follicular neoplasms of thyroid.

摘要

这是一项回顾性研究，旨在探讨核仁组成区嗜银蛋白（AgNOR）在术前细针穿刺（FNA）涂片鉴别甲状腺滤泡癌和腺瘤中的作用。本研究选取了19例经组织病理学证实的滤泡性腺瘤和癌病例。对May-Grünwald-Giemsa染色涂片进行检测，并采用AgNOR染色技术。滤泡癌与腺瘤之间（P <.05）以及滤泡癌与对照病例之间（P <.01）的AgNOR值存在显著差异。因此，AgNOR技术在鉴别甲状腺滤泡性肿瘤的良恶性方面可能具有一定作用。