脐内注射缩宫素治疗胎盘滞留

Intraumbilical oxytocin for management of retained placenta.

作者信息

Makkonen M, Suonio S, Saarikoski S

机构信息

Department of Obstetrics and Gynecology, Kuopio University Hospital, Finland.

出版信息

Int J Gynaecol Obstet. 1995 Feb;48(2):169-72. doi: 10.1016/0020-7292(94)02271-y.

DOI:10.1016/0020-7292(94)02271-y

PMID:7540566

Abstract

OBJECTIVE

The purpose of the study was to investigate the removal of a retained placenta.

METHOD

Oxytocin was injected into the vein of the umbilical cord. A total of 109 patients with retention of the placenta were randomized into two groups. Active management of the third stage of labor was carried out by giving oxytocin 5 IU intravenously and ergometrine maleate 0.2 mg intramuscularly after delivery of the fetus. Group 1, which comprised 68 patients, was allocated to receive 50 IU oxytocin diluted in 10 ml 0.9% sodium chloride solution, and the 41 patients in group 2 were given 20 ml plasma expander (dextran 70) into the umbilical vein.

RESULTS

Forty-nine cases (72%) in the oxytocin group and 22 cases (54%) in the dextran 70 group required manual removal of the retained placenta. No significant differences were found between group 1 (oxytocin) and group 2 (dextran 70).

CONCLUSION

Our results indicate that intraumbilical vein injection of oxytocin is not effective for removal of a retained placenta.

摘要

目的

本研究旨在探讨残留胎盘的清除方法。

方法

将催产素注入脐带静脉。109例胎盘残留患者被随机分为两组。胎儿娩出后，通过静脉注射5 IU催产素和肌肉注射0.2 mg马来酸麦角新碱对第三产程进行积极处理。第1组由68例患者组成，被分配接受用10 ml 0.9%氯化钠溶液稀释的50 IU催产素，第2组的41例患者则通过脐静脉给予20 ml血浆扩容剂（右旋糖酐70）。